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. 2016 Oct 4;2016:3453059. doi: 10.1155/2016/3453059

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Copyright © 2016 Lei Pang et al.

This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Inhibition of COX-2 activity reduced H/R-induced proinflammatory cytokines expression in H9C2 cardiomyocytes. mRNA expression of proinflammatory genes (IL1β, IL6, and TNFα) in H9C2 cardiomyocytes subjected to H/R stimulation in the presence or absence of NS398. mRNA levels are expressed against those in H9C2 cardiomyocytes with no stimulation. Data are shown as means ± SEM; ^∗ P < 0.05 CTL versus H/R or H/R + NS398, ^# P < 0.05 H/R versus H/R + NS398 (one-way ANOVA followed by Tukey's test); n = 6 per group.