Table 2. Major clinical trials with NOACs reporting data in patients ≥ 75 years old and atrial fibrillation.

Dabigatran	Rivaroxaban	Apixaban	Edoxaban
BIBR 1048[32]	ROCKET-AF[19]	ARISTOTLE[20]	Edox-P2[36]
PETRO[33]	J-ROCKET AF[34]	ARISTOTLE-J[35]	Edox-P2A[37]
RE-LY[18]			Edox-J[38]
			Engage-AF-TIMI 48[21]

NOACs: novel oral anticoagulants.