Table 1.
Demographic, cognitive and affective measures for healthy participants treated with either standard placebo or 0.5 mg pramipexole.
| Treatment group | ||
|---|---|---|
| Variable | Placebo | Pramipexole |
| N | 20 subjects | 20 subjects |
| Age | 20.50 ± 1.28 years | 20.80 ± 0.95 years |
| Sex | 8 males, 12 females | 8 males, 12 females |
| Education | 15.40 ± 1.05 years | 15.55 ± 0.89 years |
| Confidence | 60% confident | 45% confident |
| Prediction | 75% correct | 70% correct |
| BDI | 9.60 ± 7.18 | 8.16 ± 5.38 |
| BAI | 8.60 ± 8.29 | 7.45 ± 6.18 |
| SAS | 11.50 ± 4.80 | 11.20 ± 3.44 |
| Happiness | 4.45 ± 0.58 | 4.47 ± 0.64 |
| Sleepiness | 10.05 ± 2.65 | 9.60 ± 3.94 |
| BIS | 62.05 ± 10.29 | 58.60 ± 11.41 |
| SSS | 19.80 ± 5.72 | 20.05 ± 4.47 |
| ANART | 118.95 ± 6.46 | 118.71 ± 4.44 |
| COWAT FAS | 40.15 ± 11.00 words | 38.60 ± 10.61 words |
| COWAT animal | 24.55 ± 1.12 words | 24.80 ± 1.33 words |
| MoCA | 27.8 ± 1.51 | 27.8 ± 1.94 |
Values are presented as group means ± SEM. All values are in units of the respective questionnaire or task scale, unless otherwise stated (N = 20). Confidence: whether the subject could confidently predict which treatment they received; Prediction: whether the subject correctly or incorrectly predicted which treatment they received; BDI, Beck Depression Inventory II; BAI, Beck Anxiety Inventory; SAS, Starkstein Apathy Scale; Happiness, Oxford Happiness Questionnaire; Sleepiness, Epsworth Sleepiness Scale; BIS, Barratt Impulsiveness Scale; SSS, Sensation-Seeking Scale; ANART, American National Adult Reading Test; COWAT FAS, Controlled Oral Word Association Test FAS Task; COWAT Animal, COWAT Animal Task; MoCA, Montreal Cognitive Assessment. All factors were analyzed using two-tailed t-tests and no significant differences were found between the two groups (p > 0.05 for all factors).