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. 2016 Oct 18;7:1615. doi: 10.3389/fmicb.2016.01615

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Copyright © 2016 Rasmussen-Ivey, Hossain, Odom, Terhune, Hemstreet, Shoemaker, Zhang, Xu, Griffin, Liu, Figueras, Santos, Newton and Liles.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Photographs of channel catfish infected by vAh showing (A) external surfaces that are exhibiting congestion/hemorrhage around the head/pectoral fin and within the eye and (B) the celomic cavity that has internal organs moderately congested and enlarged, a congested/hemorrhagic spleen (green arrow), and multifocal pale foci corresponding to areas of necrosis (yellow arrow) scattered over the liver (photographs courtesy of Dr. Wes Baumgartner, Mississippi State University) as well as photomicrographs of a channel catfish infected by vAh strain ML09-119 showing (C) a section of spleen with splenic ellipsoids (arrows) that are edematous and ellipsoidal arteries that are lined by degenerating as well as necrotic endothelial cells and (D) a section of liver with edema and necrosis of pancreatic acinar tissue surrounding branches of the hepatic portal vein (arrows).