Table 4.

Virulence factors that are unique to vAh strains, based on a comparison of significant BLASTn hits between A. hydrophila isolates against the RAST/SEED database.

Subsystem	Role	GI
Glycine/serine Utilization	L-serine dehydratase	958619257
Inositol catabolism	5-deoxy-glucuronate isomerase	958618826
Inositol catabolism	5-keto-2-deoxygluconokinase	827371814
Inositol catabolism	Epi-inositol hydrolase	612156152
Inositol catabolism	Inositol transport system ATP-binding protein	958621246
Inositol catabolism	Inositol transport system permease protein	958620586
Inositol catabolism	Inositol transport system sugar-binding protein	657060685
Inositol catabolism	Inosose dehydratase	507222178
Inositol catabolism	Myo-inositol 2-dehydrogenase 1	656991783
Inositol catabolism	Myo-inositol 2-dehydrogenase 2	827371809
Inositol catabolism	Transcriptional regulator of the myo-inositol catabolic operon	958618669
Sialic Acid Metabolism	N-acetylmannosamine kinase	827373367
Sialic Acid Metabolism	N-acetylneuraminate lyase	1043232173
Sialic Acid Metabolism	Predicted sialic acid transporter	446588390
Sialic Acid Metabolism	Sugar isomerase involved in processing of sialic acid	958620857
Pyridoxin Biosynthesis	Predicted transcriptional regulator of pyridoxine metabolism	16078013
Phage DNA synthesis	DNA adenine methyltransferase, phage-associated	67483065
Phage capsid proteins	Phage capsid scaffolding protein	516389014
Phage capsid proteins	Phage major capsid protein	507220251
Phage lysis modules	Phage lysin, 1,4-beta-N-acetylmuramidase	511291760
Phage packaging machinery	Phage portal protein	958618794
Phage packaging machinery	Phage terminase small subunit	759443491
Phage packaging machinery	Phage terminase, large subunit	958620694
Queuosine-Archaeosine Biosynthesis	Queuosine biosynthesis QueD, PTPS-I	1043232409
Queuosine-Archaeosine Biosynthesis	archaeosine tRNA-ribosyltransferase type 5	507221161