Table 1.
Characteristics | vanA | vanB | vanC | vanD | vanE | vanG | vanL | vanM | vanN |
---|---|---|---|---|---|---|---|---|---|
Enterococcus species | E. faecium; E. faecalis | E. faecium; E. faecalis | E. gallinarum, E. casseliflavus, E. flavescens | E. faecium | E. faecalis | E. faecalis | E. faecalis | E. faecium | E. faecium |
Vancomycin MIC (μg/mL) | 64–1024 | 4–1024 | 2–32 | 16–64 | 16–32 | 16–32 | 8 | >256 | 16 |
Teicoplanin MIC (μg/mL) | 16–512 | < 1 | < 1 | 2–16 | < 0.5 | < 0.5 | < 0.5 | 96 | 0.5 |
Genetic determinant | acquired | acquired | intrinsic | acquired | acquired | acquired | acquired | acquired | acquired |
transferable | Yes | Yes | No | No | No | No | No | Yes | Yes |
New precursor of ligase | D-ala-D-lac | D-ala-D-lac | D-ala-D-ser | D-ala-D-lac | D-ala-D-ser | D-ala-D-ser | D-ala-D-ser | D-ala-D-lac | D-ala-D-ser |
Expression | Inducible | Inducible | constitutive | constitutive | Constitutive or inducible | Constitutive or inducible | Constitutive or inducible | Inducible | constitutive |