Figure 7. Antibiotic-treated mice have altered expression of dopamine and glutamate-related transcripts in the NAc.
Mice with antibiotic-induced reductions in gut bacteria (Abx) demonstrate increased levels of Drd1 (a) and Gria2 (c) in the NAc following treatment with cocaine; control animals, H2O. Levels of Drd2, Dlg4, Grin2a and Grin2b were unaltered. (*p < 0.05; **p < 0.01; n = 9–12/group).