TABLE 3.
B. burgdorferi lacking bb0318 displays qualitative measures of infection at a dose of 1 × 107 spirochetes
| Clone genotype | No. of positive mice/no. of mice analyzed as determined by: |
|||
|---|---|---|---|---|
| Serologya | Reisolation of spirochetes from tissuesb |
|||
| Ear | Bladder | Joint | ||
| Wild type | 6/6 | 6/6 | 6/6 | 6/6 |
| Δbb0318/pBSV2G | 5/6 | 4/6 | 4/6 | 5/6 |
| Δbb0318/pBSV2G bb0318 | 6/6 | 5/6 | 6/6 | 6/6 |
a
Determined 3 weeks postinoculation by serological response to B. burgdorferi proteins.
b
Assessed 3 weeks postinoculation. A mouse was considered infected if spirochetes were reisolated from at least one of the three tissues analyzed.