FIG 9.

Y. enterocolitica ΔyopH promotes Y. enterocolitica WT clearance during coinfection. C57BL/6 mice were infected with 5 × 10⁸ CFU Y. enterocolitica WT or with an equal mixture of the WT and ΔyopH strains (2.5 × 10⁸ CFU of each strain). At day 3 after infection, the bacterial load of the WT was determined in Peyer's patches (PP) (A) and feces (B). The data in panels A and B are the summary results of 2 experiments. Each symbol represents an individual mouse; horizontal lines indicate the means (***, P < 0.001). (C) Immunofluorescence analysis of abscess at day 3 after Y. enterocolitica WT-GFP infection or Y. enterocolitica WT-GFP and Y. enterocolitica ΔyopH coinfection. Neutrophil infiltration was detected with Ly6G-PE antibody (red). Photographs are representative of 1 of 4 mice per group in 2 independent experiments.