. 2016 Oct 15;194(8):1007–1014. doi: 10.1164/rccm.201511-2178OC

Table 3.

Adjusted Hazard Ratios for the Association of FEV₁ (per Decrease of 200 ml) with All-Cause Mortality

	AHI (Events/h)
	<5	≥5
N	3,318	2,825
Person-years	36,765	29,983
Deaths	670	777
Mortality rate^*	18.2	26.9
Hazard ratios for FEV₁/200 ml
Model 1^†	1.21 (1.19–1.24)	1.13 (1.12–1.16)
Model 2^‡	1.11 (1.09–1.14)	1.08 (1.05–1.10)
Model 3^§	1.10 (1.08–1.13)	1.06 (1.04–1.09)

Definition of abbreviation: AHI = apnea–hypopnea index.

P values for the interaction term between AHI and FEV₁ in models 1, 2, and 3: <0.0001, 0.029, and 0.015.

Chi-square values for likelihood ratio test for inclusion of interaction term in models 1, 2, and 3 were 18.8 (P < 0.0001), 6.12 (P < 0.013), and 7.10 (P < 0.0077).

Mortality rate per 100,000 person-years.

^{^†}

Model 1: FEV₁ (continuous), AHI (categorical), FEV₁ (continuous) × AHI (categorical) interaction.

^{^‡}

Model 2: Includes the variables from model 1 along with age, sex, race, body mass index, and smoking status.

^{^§}

Model 3: Includes the variables from model 2 along with hypertension and cardiovascular disease.