Table 3.
The clinical site of infection in children with Klebsiella pneumoniae bloodstream infection
| Clinical site of infection | All | ESBL | Non-ESBL | p value |
|---|---|---|---|---|
| n/N (%) | n/N (%) | n/N (%) | ||
| No. with primary bloodstream infection without a definable focus | 206/410 (50.5) | 159/339 (46.9) | 47/71 (66.2) | 0.004 |
| Common sites of infection | ||||
| Pneumonia | 122 (29.8) | 108 (31.9) | 14 (19.7) | 0.04 |
| Vascular-catheter related | 20 (4.9) | 19 (5.6) | 1 (1.4) | 0.13 |
| Peritonitis | 20 (4.9) | 16 (4.7) | 4 (5.6) | 0.76 |
| UTIa | 20 (4.9) | 16 (4.7) | 4 (5.6) | 0.76 |
| Septic wound and soft tissue | 23 (5.7) | 21 (6.2) | 2 (2.8) | 0.26 |
| NECb | 20 (4.9) | 18 (5.3) | 2 (2.8) | 0.37 |
| Septic drip site (+vec culture of KP) | 12 (2.9) | 11 (3.2) | 1 (1.4) | 0.4 |
| Cholangitis | 4 (1.0) | 4 (1.2) | 0 | N/S |
| Dysentery | 3 (0.7) | 2 (0.6) | 1 (1.4) | 0.4 |
| Typhilitis | 3 (0.7) | 3 (0.9) | 0 | N/S |
| Bacterial endocarditis | 1 (0.2) | 1 (0.3) | 0 | N/S |
| Necrotic tumour | 1 (0.2) | 1 (0.3) | 0 | N/S |
| Bowel obstruction | 1 (0.2) | 1 (0.3) | 0 | N/S |
n/N stratum specific proportions, UTI a urinary tract infection, NEC b, necrotising enterocolitis, +ve c positive, ESBL extended-spectrum-β-lactamase-producing Klebsiella pneumoniae