Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
TSC2 loss in patient-derived HCC cell could predict everolimus efficacy. (A) Western blot analysis of three HCC cell lines with indicated antibodies. YSY cell line, expressed low TSC2 protein level, showed decreasing the phosphorylation of mTOR by everolimus. (B) Drug sensitivity to everolimus. IC50 values of KKS, KHK, and YSY cell were >10, >10, and 1.5 μM, respectively. (C) Graphs of everolimus IC50 values of three HCC cells.
