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. Author manuscript; available in PMC: 2017 Jul 25.
Published in final edited form as: Chem Soc Rev. 2016 Jul 25;45(15):4074–4126. doi: 10.1039/c5cs00287g

Figure 16. Microarrays hybridized with cDNA made from rat total RNA.

Figure 16

a) Result from cDNA labeled with Cy5-dCTP control. b) Result from cDNA labeled with biotin-functionalized dCTP and dUTP followed by binding with NeutrAvidin-functionalized CPMV-Cy5. Both strategies resulted in a density of labeling of about one every 50 bases, but the CPMV-based probe resulted in greater sensitivity, detecting 71% of the features compared to 57% for the control. Reproduced with permission from ref. 390. Copyright 2009 Elsevier.