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. Author manuscript; available in PMC: 2017 Jul 25.
Published in final edited form as: Chem Soc Rev. 2016 Jul 25;45(15):4074–4126. doi: 10.1039/c5cs00287g

Figure 21. Ordered assembly of phage trimer by DNA hybridization.

Figure 21

a) Diagram of design of multiphage structure using DNA hybridization. pIX protein displaying DNA sequence A and pIII protein displaying sequence B are linked by complementary sequence C. Similiarly, pIX and pIII proteins displaying sequences D and E, respectively, are linked by complementary sequence F. b) Fluorescence microscopy image of phages after assembly illustrated the specific arrangement of the phages. Reproduced with permission from ref. 515. Copyright 2013 American Chemical Society.