TABLE 4.

Gene ontology enrichment analysis of the DEGs from anaerobic RNA-Seq of UA159 versus ΔcidB mutant using DAVID and REVIGO tools^a

Gene category	Term ID and GO	Functional description	EASE score
Upregulated	[GOTERM_CC] GO:0030312	External encapsulating structure	2.25E−02
	[GOTERM_MF]
	GO:0019842	Vitamin binding	6.40E−03
	GO:0043176	Amine binding	3.87E−04
	GO:0000036	ACP phosphopantetheine attachment site binding involved in fatty acid biosynthetic process	6.46E−09
	GO:0048037	Cofactor binding	1.20E−04
	GO:0031406	Carboxylic acid binding	2.86E−03
	GO:0016597	Amino acid binding	3.87E−04
	GO:0031177	Phosphopantetheine binding	5.77E−06
Downregulated	[GOTERM_BP] GO:0055114	Oxidation reduction	3.38E−02

^aEASE score, a modified Fisher exact P value; GO, gene ontology; BP, biological process; CC, cellular component; MF, molecular function; ACP, acyl carrier protein. Bold indicates cluster-representative terms.