Table 3.
Variable | FGFR1a | FGFR2a | FGFR3b |
---|---|---|---|
FGFR1a | NA | pos, p = 0.0005 | pos p = 0.24 |
FGFR2a | pos, p = 0.0005 | NA | neg p = 0.83 |
FGFR3b | pos, p = 0.21 | neg, p = 0.61 | NA |
Genderc | pos, p = 0.46 | pos, p = 0.01 | neg, p = 0.69 |
Age at diagnosisd | pos, p = 0.50 | neg, p = 0.26 | pos, p = 0.17 |
Smoking statuse | neg, p = 0.17 | pos, p = 0.58 | pos, p = 0.008 |
SCC versus AC | neg, p = 0.002 | neg, p < 10−7 | pos, p < 10−6 |
LCC versus AC | neg, p = 0.47 | neg, p = 0.10 | pos, p = 0.15 |
Tumour stage | pos, p = 0.31 | neg, p = 0.30 | neg, p = 0.98 |
Direction of association and adjusted p‐values are given.
Per 10%‐point increase.
Dichotomized into negative (0) and positive (1+/2+).
Female versus male.
Per year.
FGFR1 and 2 as heavy versus light smoking; FGFR3 as PY.
SCC, squamous cell carcinoma; AC, adenocarcinoma; LCC, large cell carcinoma.