Table 4.

Histological features of the FGFR3‐TACC3 translocated and FGFR3 amplified non‐small cell lung cancer samples

Sample	FGFR3‐TACC3 positive 3.0% (6/200)	FGFR3 amplification 4.7% (2/43)	FGFR3 IHC	Histology	FGFR1 IHC	FGFR2 IHC
1	yes	no	High	SCC	Low	Medium
2	yes	no	High	SCC	Low	Negative
3	yes	no	Low	SCC	Low	Negative
4	yes	no	Low	AC	Low	Medium
5	yes	no	Negative	SCC	Low	Negative
6	yes	no	Negative	AC	Medium	Medium
7	no	yes	High	SCC	High	Negative
8	no	yes	Low	SCC	Low	Low

Sample #2 and #6 showed a FGFR3 gain by FISH.