Table 1. Serum lipid profile and SBP in Apoe−/− mice.
| AL-Con (n) | CR-Con (n) | AL-AngII (n) | CR-AngII (n) | |
|---|---|---|---|---|
| TG (mmol/liter) | 0.35 ± 0.03 (16) | 0.17 ± 0.06a (13) | 0.42 ± 0.04 (16) | 0.08 ± 0.02b (15) |
| TC (mmol/liter) | 11.05 ± 0.75 (16) | 9.57 ± 0.64 (13) | 10.84 ± 1.13 (16) | 11.48 ± 1.07 (15) |
| HDL-C (mmol/liter) | 0.51 ± 0.05 (16) | 0.47 ± 0.04 (13) | 0.56 ± 0.07 (16) | 0.45 ± 0.03 (15) |
| LDL-C (mmol/liter) | 2.5 ± 0.28 (16) | 2.22 ± 0.14 (13) | 2.29 ± 0.3 (16) | 2.77 ± 0.28 (15) |
| SBP (mmHg) | 108 ± 3.8 (10) | 102.2 ± 3.9 (11) | 134.2 ± 6.7c (9) | 129.6 ± 6.5d (9) |
The data are shown as the means ± SEM. Sample sizes (n) are shown in parenthesis. P-values were obtained using one-way ANOVA plus a posthoc analysis using a Bonferroni test in total cholesterol (TC) and SBP or by a Kruskal-Wallis test plus a posthoc analysis using a Dunn’s multiple comparison test in triglyceride (TG), high-density lipoprotein-cholesterol (HDL-C), and low-density lipoprotein-cholesterol (LDL-C).
a
P < 0.05 versus the AL-Con group.
b
P < 0.01 versus the AL-AngII group.
c
P < 0.01 versus the AL-Con group.
d
P < 0.01 versus the CR-Con group.