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. 2016 Sep 28;113(41):11414–11419. doi: 10.1073/pnas.1601306113

Fig. 1.

Fig. 1.

Washout by flow and possible counteracting factors. (A) Flow alone leads to emptying of channel content over time. Additional factors are required to counteract this washout and help to maintain a stable bacterial density over time. Such factors may include: (B) active motility by bacteria to swim toward the nutrient source; (C) wall growth; and (D) peristaltic mixing, with backflow generated by contractions of colonic walls.