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Survey of neurodegeneration in the brain of mutant PFN1 mice. Nissl staining reveals no obvious difference in the cerebral and cerebellar cortices among nTg, PFN1WT, and PFN1C71G mice. However, an increased cellulation is observed in the medulla of PFN1C71G mice compared with nTg and PFN1WT mice. GCL, granule cell layer; ML, molecular layer; PC = Purkinje cell.
