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. 2016 Oct 12;11:5335–5347. doi: 10.2147/IJN.S116288

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© 2016 Huang et al. This work is published and licensed by Dove Medical Press Limited

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Quantitative detection of methylation status of PAX1 gene by novel methods.

Notes: (A) Curve fitting between methylated DNA rate and absorbance ratio A₆₅₀/A₅₂₀. (B) Changes of UV–vis spectra of AuNPs with different percentages of methylated DNA and unmethylated DNAs within 6 mins. (C) Six minutes after the addition of NaCl, the color of AuNPs colloid solution for various percentages of mixed PAX1^m⁺.

Abbreviations: AuNPs, gold nanoparticles; UV-vis, ultraviolet-visible spectrophotometry.