Table 2.

Suggested reading to further increase the understanding about the chances and odds to develop vanadium-containing antidiabetic drugs.

Review title	Comments	Ref.
Historic perspective and recent developments on the insulin-like actions of vanadium; toward developing vanadium-based drugs for diabetes	To further the reader’s insight about the biochemical aspects of the insulin signaling cascade, metabolic effects and molecular mechanisms of vanadium actions.	[2]
Are Vanadium Compounds Drugable? Structures and Effects of Antidiabetic Vanadium Compounds: A Critical Review	At the time of writing, many details were still under debate and the present bibliographic study answers the question raised. (Of note, typing error in the original title’s word “druggable”.)	[86]
Vanadium in diabetes: 100 years from Phase 0 to Phase I	A chronological synopsis of the mayor cornerstones in antidiabetic vanadium research spanning the time of over one hundred years.	[20]
An evidence-based systematic review of vanadium by the Natural Standard Research Collaboration	The review evaluates the problems with vanadium concerning efficacy, physiological interactions and safety issues.	[112]
The future of/for vanadium	The review study covers a wide range of natural sites and life forms which contain vanadium or bio-transformed molecular components bearing it.	[21]
Recent Advances in PTP1B Inhibitor Development for the Treatment of Type 2 Diabetes and Obesity (book chapter 6)	The electronic book provides an excellent synopsis about 15 new chemical classes of antidiabetic agents under development. Albeit, book chapter 6 about PTP1B target dedicates merely one single phrase to vanadium complexes: “Vanadium compounds, which are potent inhibitors of PTPs including PTP1B, also displayed insulin mimetic or enhancing effects”.	[150]
Thirty years through vanadium chemistry	The important scientific landmarks (events) are reported to form a historical description about the discoveries made concerning biochemical functions, pathways and cellular reactions, along with the discoveries of new structures, their studies as well as the role of speciation for vanadium-containing compounds in aqueous solution and in biological fluids among other issues relevant for the Medicinal Chemist.	[123]