Table 1.
Compound 13 | KM | VMAX | R2 |
---|---|---|---|
(μM) | (μM) | (μM) | |
0 | 3 +/- 1 | 210 +/- 11 | 0.9 |
25 | 11 +/- 3 | 243 +/- 20 | 0.87 |
50 | 38 +/- 6 | 354 +/- 26 | 0.97 |
100 | 145 +/- 30 | 631 +/- 94 | 0.98 |
Compound 25 | KM | VMAX | R2 |
(μM) | (μM) | (μM) | |
0 | 3 +/- 1 | 296 +/- 17 | 0.88 |
25 | 11 +/-3 | 307 +/- 30 | 0.83 |
50 | 23 +/- 6 | 344 +/- 34 | 0.91 |
100 | 79 +/- 15 | 542 +/- 60 | 0.98 |
2-BP | KM | VMAX | R2 |
(μM) | (μM) | (μM) | |
0 | 4 +/- 1 | 222 +/-7 | 0.96 |
25 | 2 +/-1 | 160 +/-5 | 0.95 |
50 | 10 +/-6 | 126 +/- 23 | 0.53 |
100 | 14 +/- 7 | 51 +/-8 | 0.71 |