FIG 4.

Longitudinal cIL-10 production mirrors viral shedding patterns. Production of cIL-10 by RhCMV antigen-stimulated PBMC (red; right ordinate) in individual animals over time was graphed alongside RhCMV genome copy number per milliliter (log₁₀) of saliva (black; left ordinate) at concurrent time points (3 to 4 per animal). The dashed lines represent the trend line determined by linear regression. This is a representative sampling of the 20 study animals (refer to Fig. S1 in the supplemental material for results of the total analysis).