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. 2015 Dec 15;5(12):e697. doi: 10.1038/tp.2015.192

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Copyright © 2015 Macmillan Publishers Limited

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DUF1220 copy number associations support autism and schizophrenia being related disorders. CON1 associations with negative symptoms in schizophrenic males, and with social/communicative symptoms in ASD, suggest these phenotypes overlap between the disorders. The inverse association between CON1 and positive symptoms suggest that positive symptoms could be considered as an opposing phenotype to ASD. ASD, autism spectrum disorder.