Table 1. CON1 associations with schizophrenia features.
Phenotype measure | Beta | s.e. | P-value |
---|---|---|---|
SAPS: total populationa | −0.097 | 0.039 | 0.013 |
SAPS: childhood onset | 0.15 | 0.15 | 0.22 |
SAPS: adolescent onset | 0.003 | 0.06 | 0.70 |
SAPS: adult onset | −0.16 | 0.05 | 0.00155 |
SANS: malesb | 0.16 | 0.07 | 0.0327 |
Abbreviations: SANS, scale for the assessment of negative symptoms; SAPS, scale for the assessment of positive symptoms.
Results from regression analyses of DUF1220 subtype CON1 copy number versus positive symptom score (SAPS), negative symptom score (SANS) stratified by age of onset. The stratified population description is available in Supplementary Table 2. P-values meeting statistical significance (<0.05) are in bold.
CON1 versus SAPS model includes SANS and age as covariates; age-specific models include SANS as a covariate.
CON1 versus SANS model includes SAPS as covariate.