Table 1. Baseline characteristics of studies included.
| Characteristic | NPHSII (n = 2,556) | ASCOT (n = 1,642) | ELSA (n = 5,389) |
|---|---|---|---|
| Age (y) | 59.2 (3.3) | 63.2 (8.3) | 65.5 (9.3) |
| Sex (male) | 100% | 85.9% | 44.4% |
| Current smokers | 27.4% | 33.5% | 14.1% |
| Systolic blood pressure (mm Hg) | 133.4 (18.1) | 164.7 (17.7) | 135.2 (18.7) |
| Diastolic blood pressure (mm Hg) | 81.8 (10.8) | 95.2 (10.2) | 75.7 (10.9) |
| Total cholesterol (mmol/l) | 5.63 (0.97) | 5.94 (1.05) | 6.00 (1.17) |
| High-density lipoprotein cholesterol (mmol/l) | 1.72 (0.59) | 1.26 (0.34) | 1.54 (0.39) |
| Low-density lipoprotein cholesterol (mmol/l) | 3.08 (1.01) | 3.85 (0.93) | 3.66 (0.97) |
| Triglycerides (mmol/l)* | 1.81 (0.93) | 1.65 (0.80) | 1.57 (0.81) (n = 5,386) |
| Apolipoprotein E (mg/l)* | 34.9 (11.0) | 49.4 (15.4) | 39.4 (12.1) |
| Apolipoprotein A (g/l) | 1.64 (0.32) | — | — |
| Apolipoprotein B (g/l) | 0.86 (0.24) | — | — |
| Lipoprotein(a) (mg/dl) | 8.1 (11.6) | — | — |
| Diabetes | 2.1% | 26.0% | 7.2% |
| Glucose (mmol/l)* | — | 6.05 (1.62) (n = 1,480) | 4.95 (0.72) |
| Body mass index (kg/m2)* | 26.4 (3.5) | 28.4 (4.0) | 27.4 (4.5) |
| Waist-to-hip ratio | — | — | 0.89 (0.08) |
| C-reactive protein (mg/dl)* | 2.38 (2.44) | — | 2.02 (2.24) |
| Haemoglobin (g/dl) | — | — | 14.3 (1.4) |
| Ferritin (ng/ml)* | — | — | 86.9 (72.4) |
| Fibrinogen (g/l)* | 2.88 (0.56) | — | 3.13 (0.68) |
Data are presented as mean (SD) or percent. Dashes indicate missing variables in the given dataset.
*Log transformed; geometric means and approximate SDs are presented.
ASCOT, Anglo-Scandinavian Cardiac Outcomes Trial; ELSA, English Longitudinal Study of Ageing; NPHSII, Northwick Park Heart Study II; SD, standard deviation.