Table 1. Patient and control baseline characteristics.
| Number | Centre (recruitment period) | Sex (M/F) | Age (years) | BMI (kg/m2) | Smoking (Y|N|NR) | Cannabis (Y|N|NR) | PANSS pos | PANSS neg | PANSS gen | CAARMS pos | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Cohort 1 (106) | 52 CT | Mannheim (2000–2009) | 27/25 | 30±8 | 23±3 | 20|32|0 | 30|21|1 | NA | NA | NA | NA |
| 54 SCZ | 32/22 | 30±10 | 23±4 | 23|21|0 | 31|20|3 | 23±5 | 24±8 | 49±10 | NA | ||
| Cohort 2 (106) | 73 CT | Magdeburg (2008–2010) | 46/27 | 32±9 | 25±4 | 20|53|0 | 2|56|15 | NA | NA | NA | NA |
| 33 SCZ | 22/11 | 31±10 | 24±4 | 24|9|0 | 9|24|0 | 21±6 | 19±9 | 43±12 | NA | ||
| Cohort 3 (39) | 23 CT | Magdeburg (2010) | 10/13 | 33±11 | 23±3 | 5|18|0 | 0|23|0 | NA | NA | NA | NA |
| 16 SCZ | 8/8 | 35±11 | 21±2 | 6|9|1 | 0|15|1 | 19±8 | 16±4 | 37±12 | NA | ||
| Cohort 4 (26) | 16 CT | Magdeburg (2010–2011) | 8/8 | 35±11 | 23±3 | 1|15|0 | 0|16|0 | NA | NA | NA | NA |
| 10 SCZ | 6/4 | 37±12 | 22 ±3 | 5|5|0 | 0|10|0 | 19±8 | 14±8 | 33±21 | |||
| Cohort 5 (54) | 40 CT | Erasmus (2004–2009) | 33/7 | 26±4 | NR | NR | NR | NA | NA | NA | NA |
| 14 SCZ | 11/3 | 24±6 | NR | 10|4|0 | 8|6|0 | 21±3 | 19±4 | 35±8 | NA | ||
| Cohort 6 (135) | 88 CT | Santander (2011–2013) | 51/37 | 33±8 | 26±4 | 51|37|0 | 22|66|0 | NA | NA | NA | NA |
| 47 SCZ | 28/19 | 30±9 | 23±5 | 24|23|0 | 20|27|0 | 24±3a | 13±6a | NR | NA | ||
| Cohort 7 (46) | 46 SCZ | Muenster (2000–2007) | 35/11 | 27±9 | NR | NR | NR | 18±7 | 18±7 | NR | NA |
| Cohort 8: USA military (369) | 184 CT | USA DoDSR (1988–2006) | 136/48 | 22±4 | NR | NR | NR | NA | NA | NA | NA |
| 75 Pre-SCZ | 67/8 | 24±5 | NR | NR | NR | NR | NR | NR | NA | ||
| 110 Pre-BD | 70/40 | 21±4 | NR | NR | NR | NR | NR | NR | NA | ||
| Cohort 9: help-seeker/prodromal (76) | 18 Pre-SCZ | Paris (2009–2013) | 11/7 | 20±3 | 21±3 | 9|8|1 | 7|11|0 | 16±7 | 17±7 | 41±11 | 13±7 |
| 58 Not pre-SCZ | 33/25 | 22±4 | 22±4 | 26|24|8 | 12|46|0 | 12±5 | 15±7 | 38±10 | 8±6 |
Abbreviations: BD, bipolar disorder; BMI, body mass index; gen, general; CAARMS, Comprehensive Assessment of At-Risk Mental State; CT, control; M/F, male/female; N, no; NA, not applicable; neg, negative; NR, not recorded; PANSS, positive and negative syndrome scale; pos, positive; SCZ, schizophrenia; Y, yes.
a
Values were obtained via conversion of SAPS and SANS scores.11
Values are presented as average±standard deviation.