Table 2. Volumes of hippocampal and medial temporal cortical regions of interest per 5-HTTLPR allele group.
Brain regional volume (mm3) |
5-HTTLPR genotype |
P | |
---|---|---|---|
ll Group (N=16), mean (s.d.) | ss/sl Group (N=20), mean (s.d.) | ||
Total brain volume | 1146.52 (92.09) | 1152.83 (120.64) | 0.86 |
Right perirhinal cortex | 0.0302 (0.0087) | 0.0317 (0.0084) | 0.61 |
Left perirhinal cortex | 0.0327 (0.0072) | 0.0356 (0.0107) | 0.33 |
Right entorhinal cortex | 0.0224 (0.0069) | 0.0222 (0.0056) | 0.95 |
Left entorhinal cortex | 0.0205 (0.0041) | 0.0227 (0.0053) | 0.17 |
Right parahippocampal gyrus | 0.0351 (0.0092) | 0.0322 (0.0045) | 0.26 |
Left parahippocampal gyrus | 0.0346 (0.0067) | 0.0334 (0.0077) | 0.62 |
Right CA1 subregion | 0.0103 (0.0028) | 0.0099 (0.0017) | 0.71 |
Left CA1 subregion | 0.0087 (0.0019) | 0.0088 (0.0019) | 0.95 |
Right CA23DG subregion | 0.0303 (0.0091) | 0.0312 (0.0062) | 0.73 |
Left CA23DG subregion | 0.0263 (0.0064) | 0.0273 (0.0062) | 0.66 |
Right subiculum subregion | 0.0116 (0.0029) | 0.0110 (0.0021) | 0.50 |
Left subiculum subregion | 0.0116 (0.0026) | 0.0109 (0.0025) | 0.40 |
Abbreviations: DG, dentate gyrus; 5-HTTLPR, serotonin transporter gene; l, long allele; s, short allele; s.d., standard deviation. CA1 and CA23DG indicate subregions of the hippocampus.