Table 2. Summary of the offspring's performance in the EPM in adulthood in MIA mice with or without n-3 PUFA interventions in peri-adolescence.
| Groups | Time spent on open arms (s) | Open arm entries | % Time spent on open arms | % Entries of open arms |
|---|---|---|---|---|
| n6-SAL | 6.51 (3.4–24.7)** | 5 (3–9) | 1.11 (0.6–4.2)** | 7.81 (5.6–13.8) |
| n6-POL | 1.4 (0.3–2.8)** | 2 (0.5–4) | 0.24 (0.05–0.5)** | 3.28 (1–5.4) |
| n3-SAL | 7.71 (3.3–11.3) | 6 (3.5–6.8) | 1.3 (0.5–1.9) | 9.94 (6.8–12.9) |
| n3-POL | 12.9 (1.6–49.6) | 4 (1.3–10.3) | 2.18 (0.3–8.4) | 5.92 (1.9–15.7) |
Abbreviations: EPM, elevated plus maze; MIA, maternal immune activation; n6-POL, prenatal PolyI:C-exposed offspring treated with n-6 PUFA; n3-SAL, prenatal saline-exposed offspring treated with n-3 PUFA; n6-SAL, prenatal saline-exposed offspring treated with n6-polyunsaturated fatty acids (n-6 PUFA) control diet; PUFA, polyunsaturated fatty acids; Sal, saline.
**P⩽0.01.
All values are median (25–75 percentiles).