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. 2015 Sep 8;5(9):e633. doi: 10.1038/tp.2015.127

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Copyright © 2015 Macmillan Publishers Limited

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Regional association plot. P-values (ordinate axis, upper panel) are from the Cochran–Armitage trend test in the discovery set (circles: genotyped single-nucleotide polymorphisms (SNPs) and squares: imputed SNPs) and combination set (diamonds: the discovery and replication sets, triangles: discovery, replication and cross-replication set) in upper panel. The blue lines indicate the recombination rates in cM per Mb estimated using HapMap samples (upper panel). A horizontal line indicates the location of the AUTS2 gene (middle panel). A linkage disequilibrium map based on r² values was computed using the Hapmap JPT+CHB data (the International HapMap Project data, bottom panel).