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. 2016 Aug 15;204(2):483–497. doi: 10.1534/genetics.116.189308

Table 5 .

Empirical type I error rate when β1=1 and all other βj=0 (j1), based on multivariate t distribution with 3 d.f., with common correlation structure

Sample size No. traits Trait correlation Nominal type I error rate
0.05 0.01
100 4 0.2 0.042 0.011
0.5 0.067 0.019
0.8 0.057 0.015
10 0.2 0.088 0.018
0.5 0.104 0.028
0.8 0.094 0.030
500 4 0.2 0.059 0.011
0.5 0.038 0.007
0.8 0.043 0.009
10 0.2 0.041 0.016
0.5 0.059 0.021
0.8 0.050 0.010
1000 4 0.2 0.052 0.006
0.5 0.047 0.006
0.8 0.054 0.009
10 0.2 0.054 0.010
0.5 0.058 0.015
0.8 0.055 0.016

Underlined values are for when empirical type I error exceeds the upper 95% C.I.