Table 8 .

Power to detect pleiotropy when associated traits have $\beta =0.2$ (explain 1.2% trait variation; power = 70% for marginal effect)

No. associated traits $\left(\beta =0.2\right)$	Trait correlation	Nominal type I error rate
		0.05	0.01
2	0.2	0.220	0.069
	0.5	0.393	0.165
	0.8	0.964	0.850
3	0.2	0.494	0.255
	0.5	0.715	0.478
	0.8	1.000	0.991
5	0.2	0.842	0.636
	0.5	0.907	0.750
	0.8	1.000	1.000

Shown is a multivariate normal distribution with equal correlation structure, for a sample size of 500 subjects and minor allele frequency of genetic variant set to 0.20.