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Effects of elimination of SLIK and SAGA and SIR2 on activation of PHO84 in rho0 cells. (A) SLIK was eliminated by the S200 mutation in SPT7. SAGA was eliminated by deletion of SPT8. SLIK and SAGA were eliminated together by combining the S200 mutant with the SPT8 deletion or by the deletion of SPT7. (B) Effect of SIR2 deletion on expression of PHO84 in rho0 cells. YPK9 is the rho+ strain and YJR2 is its rho0 derivative.
