Table 1. The demographic of schizophrenia patients and the non-psychiatric controls in the peripheral blood cohort and the postmortem brain cohort.
| Variable |
Peripheral blood cohort |
|
|---|---|---|
| Schizophrenia (N=48) | Controls (N=37) | |
| N (%) | N (%) | |
| Gender | ||
| Female | 23 (47.9) | 23 (62.2) |
| Male | 25 (52.1) | 14 (37.8) |
| Mean (s.d.) | Mean (s.d.) | |
| Education (years)a | 11.3 (2.9) | 17.1 (3.5) |
| Age | 40.2 (10.7) | 38.0 (10.8) |
| Age at onset | 23.6 (7.0) | — |
| Duration of illness | 16.8 (10.5) | — |
| Chlorpromazine equivalent (mg daily) | 453.3 (276.1) | — |
|
Postmortem brain cohort |
||
|---|---|---|
| Schizophrenia (N=25) | Controls (N=27) | |
| N (%) | N (%) | |
| Gender | ||
| Female | 4 (16.0) | 5 (19.5) |
| Male | 21 (84.0) | 22 (81.5) |
| Suicideb | ||
| Yes | 9 (36.0) | 0 (0.0) |
| No | 16 (64.0) | 27 (100.0) |
| Mean (s.d.) | Mean (s.d.) | |
| Age | 43.4 (18.3) | 43.3 (18.1) |
| Age at onset | 25.6 (9.8) | — |
| Duration of illness | 17.5 (15.4) | — |
| PMI (h) | 40.4 (12.4) | 41.4 (15.2) |
| Brain pH | 6.3 (0.2) | 6.3 (0.2) |
| RIN | 8.3 (0.7) | 8.5 (0.5) |
| Chlorpromazine equivalent (mg daily) | 651.8 (628.5) | — |
Abbreviations: PMI, postmortem interval; RIN, RNA integrity numbers.
a
P<0.001 based on t-test.
b
P<0.0001 based on Fisher's exact test.