Table 1. Genetic interactions of MEI-1 pathway components.
Temperature | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|
15° | 20° | 25° | ||||||||
Maternal Genotypea | % Hatch | Fold Change | % Male | % Hatch | Fold Change | % Male | % Hatch | Fold Change | % Male | |
1 | cul-2(ts) | 64 | 0.5 | 51 | 2.6 | |||||
2 | mel-26(null) | 12 | ||||||||
3 | cul-2(ts); mel-26(null) | 0.7 | 11 × ↓ | |||||||
4 | tbb-2b | 100 | 0 | |||||||
5 | cul-2(ts) tbb-2 | 40 | 1.6 × ↓ | 2.6 | 27 | 1.9 × ↓ | 6.0 | |||
6 | rfl-1(ts) | 89 | 72 | |||||||
7 | rfl-1(ts); mel-26(null) | 0.9 | 12 × ↓ | |||||||
8 | mel-26(null); tbb-2 | 68 | 7.8 × ↑ | |||||||
9 | rfl-1(ts); tbb-2 | 92 | ||||||||
10 | rfl-1(ts); mel-26(null); tbb-2 | 65 | 77 × ↓ | |||||||
11 | mbk-2(ts) | 87 | 59 | |||||||
12 | rfl-1(ts); mbk-2(ts) | 35 | 2.2 × ↓ | 0.5 | 85 × ↓ | |||||
13 | mbk-2(ts); tbb-2 | 78 | ||||||||
14 | rfl-1(ts); mbk-2(ts); tbb-2 | 1.5 | ||||||||
15 | hecd-1 | 89 | 96 | 0 | 77 | 0 | ||||
16 | hecd-1; mel-26(null) | 0c | > 190 × ↓ | |||||||
17 | hecd-1(RNAi) | 99 | 99 | |||||||
18 | hecd-1(RNAi); mel-26(null) | 0c | > 150 × ↓ | |||||||
19 | hecd-1; tbb-2 | 91 | 85 | 0.4 | ||||||
20 | hecd-1(RNAi); mel-26(null); tbb-2 | 50 | ||||||||
21 | mei-1(gf) | 12 | ||||||||
22 | hecd-1(RNAi); mei-1(gf) | 0c | > 60 × ↓ | |||||||
23 | mbk-2(ts) | 74 | ||||||||
24 | hecd-1; mbk-2(ts) | 81 | ||||||||
25 | mei-2(sb39ts) | 78 | 1.3 | 41 | 2.2 | |||||
26 | hecd-1; mei-2(sb39ts) | 28 | 2.5 × ↓ | 3.4 | 8 | 4.9 × ↓ | 13 | |||
27 | mei-2(ct98) | 71 | 2.6 | |||||||
28 | hecd-1; mei-2(ct98) | 19 | 2.9 × ↓ | 8.9 | ||||||
29 | cul-2(ts); hecd-1 | 16 | 3.5 × ↓ | 2.3 | 11 | 4.4 × ↓ | 12 |
ts alleles are presumed hypomorphs at intermediate temperatures. hecd-1 = ok1437, cul-2(ts) = or209, mbk-2(ts) = dd5, mei-1(ts) = or1178, mei-1(gf) = ct46, mel-26(null) = ct61sb4, mel-26(ts) = or184, rfl-1(ts) = or198, and tbb-2 = sb26.
Data from Lu et al. (2004).
N values for lines 16, 18, and 22 are 1587, 1290, and 501, respectively. Fold enhancement is calculated based on if one embryo had hatched.