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. Author manuscript; available in PMC: 2016 Oct 18.
Published in final edited form as: Nat Genet. 2016 Jul 25;48(9):1049–1054. doi: 10.1038/ng.3620

Figure 1.

Figure 1

Association results from genome-wide and targeted sequencing and beanplots of BMI versus genotype in men and women from the discovery sample. (a) Manhattan plot of the genome-wide association scan for association with BMI. The red line corresponds to a P value of 5 × 10−8. (b) Association results using imputed data for the region encompassing CREBRF. The strength of LD, as measured by the squared correlation of genotype dosages, between each variant and the missense variant rs373863828 is represented by the color of each point. The red line corresponds to a P value of 5 × 10−8. The plot was generated using LocusZoom32. (c) Beanplots of BMI versus genotype in men (n = 1,233) and women (n = 1,833) from the discovery sample. Each bean consists of a mirrored density curve containing a one-dimensional scatterplot of the individual data. A solid line shows the average for each group, and the dashed line represents the overall average. The plot was generated using the R beanplot package33.