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. Author manuscript; available in PMC: 2017 Oct 11.
Published in final edited form as: Circulation. 2016 Sep 14;134(15):1085–1099. doi: 10.1161/CIRCULATIONAHA.116.023003

Figure 5. Cardiomyocyte (LV) passive stiffness and slack sarcomere length.

Figure 5

(A) Skinned cardiomyocyte passive stiffness was increased in cRbm20ΔRRM-DMSO but was reduced in cRbm20ΔRRM-raloxifene mice. (For analysis, see Supplemental Methods.) ****p≤0.0001 vs. Sham; ####p≤0.0001 vs. cRbm20ΔRRM-DMSO. (B) Slack sarcomere length of skinned cardiomyocytes (see text for details). ****p≤0.0001 (n=13, 15, 19 cells from 6, 6, 7 mice).

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