Skip to main content
. Author manuscript; available in PMC: 2017 Oct 11.
Published in final edited form as: Circulation. 2016 Sep 14;134(15):1085–1099. doi: 10.1161/CIRCULATIONAHA.116.023003

Figure 6. Cardiomyocyte dimensions at diastasis.

Figure 6

(A) Representative confocal immunofluorescent images of LV wall tissue at diastasis. Red: laminin and connexin43, green: alpha-actinin, and blue: nucleus. (B) Comparison of cell dimension in sham and two TAC/DOCA groups (DMSO and raloxifene). Cardiomyocytes of both TAC/DOCA groups are longer and wider than in sham and consequently have a larger area. However, cardiomyocytes of cRbm20ΔRRM-raloxifene are smaller than cRbm20ΔRRM-DMSO. SL of cRbm20ΔRRM-raloxifene is longer than sham and cRbm20ΔRRM-DMSO. **p≤0.01, ****p≤0.0001 vs. Sham;##p≤0.01, ###p≤0.001, ####p≤0.0001 vs. cRbm20ΔRRM-DMSO group. (n= 631, 580, 634 cells for cell dimension and 75, 79, 93 cells for SL measurement in 4, 4, 3 hearts).

HHS Vulnerability Disclosure