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Cytopathic effect induced by CNGV. KFCs were infected with CNGV and incubated at a permissive temperature of 22°C. At 4 to 5 days p.i., cytopathic effect can be observed. Cells become enlarged and develop abundant endoplasmic vacuoles (center box; the inset at upper right shows the boxed area at a higher magnification). The arrow indicates uninfected cells.
