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Ovariectomy (OVX) increases FNDC5 mRNA and protein content. mRNA expression of PGC-1α (a) and FNDC5 (c). Western blot and densitometric analysis of PGC-1α (b) and FNDC5 (d) in skeletal muscle of sham-operated and ovariectomized (OVX) female Wistar rats, n = 6/group. *p ≤ 0.05 OVX versus sham, **p ≤ 0.01 OVX versus sham
