Table 4.
Rates of mortality, brain death and organ donation in the included studies
| Author, year [reference] | No. of patients | Mortality, n (%) | Brain death rate | Organ donation rate | ||||
|---|---|---|---|---|---|---|---|---|
| n | % Of total patients | % Of deaths | n | % Of brain deaths | % Of deaths | |||
| c-CPR | ||||||||
| Adrie, 2008 [8] | 246 | 210 (85) | 40 | 16.3 | 19.0 | 19 | 47.5 | 9.1 |
| Bernard, 2002 [14] | 77 | 45 (58) | 2 | 2.6 | 4.4 | |||
| Calderon, 2014 [26] | 72 | 46 (64) | 8 | 11.1 | 17.4 | |||
| Dragancea, 2013 [6] | 159 | 84 (53) | 4 | 2.5 | 4.8 | 4 | 100 | 4.8 |
| Elmer, 2016 [27] | 4265 | 2775 (65) | 305 | 7.2 | 11.0 | |||
| Geocadin, 2006 [5] | 58 | 48 (83) | 1 | 1.7 | 2.1 | |||
| Greer, 2013 [28] | 200 | 180 (90) | 20 | 10.0 | 11.1 | |||
| Grossestreuer, 2013 [29] | 194 | 109 (56) | 4 | 2.1 | 3.7 | |||
| Lemiale, 2013 [4] | 1152 | 768 (67) | 94 | 8.2 | 12.2 | |||
| Mentzelopoulos, 2013 [30] | 268 | 149 (56) | 0 | 0 | 0 | |||
| Mulder, 2014 [31] | 154 | 78 (51) | 8 | 5.2 | 10.3 | |||
| Nielsen, 2013 [32] | 939 | 411 (44) | 18 | 1.9 | 4.4 | |||
| Peberdy, 2003 [33] | 14,720 | 12,217 (83) | 1177 | 8.0 | 9.6 | 159 | 13.5 | 1.3 |
| Rundgren, 2010 [34] | 95 | 43 (45) | 3 | 3.2 | 7.0 | 3 | 100 | 3.2 |
| Sivaraju, 2015 [35] | 100 | 71 (71) | 7 | 7.0 | 9.9 | |||
| Stammet, 2009 [36] | 45 | 22 (49) | 3 | 6.7 | 13.6 | |||
| Total c-CPR | 22,744 | 17,256 (75.9) | 1694 | 5.4 [3.9–7.1] | 8.3 [6.5–10.4] | 185 | 59.2 [18.0–95.7] | 4.8 [0.4–11.5] |
| e-CPR | ||||||||
| Avalli, 2012 [37] | 42 | 31 (73.8) | 12 | 28.6 | 38.7 | 5 | 41.7 | 16.1 |
| Fagnoul, 2013 [38] | 24 | 18 (75.0) | 5 | 20.8 | 27.8 | 1 | 20 | 5.6 |
| Lamhaut, 2013 [39] | 7 | 6 (85.7) | 3 | 42.9 | 50 | 2 | 66.7 | 33.3 |
| Le Guen, 2011 [40] | 51 | 49 (96.1) | 10 | 19.6 | 20.4 | |||
| Massetti, 2005 [41] | 40 | 32 (80) | 15 | 37.5 | 46.9 | |||
| Megarbane, 2007 [42] | 17 | 14 (82.4) | 1 | 5.9 | 7.1 | |||
| Megarbane, 2011 [43] | 66 | 65 (98.5) | 6 | 9.1 | 9.2 | 3 | 50 | 4.6 |
| Pozzi, 2016 [44] | 68 | 62 (91.2) | 14 | 20.6 | 22.6 | 0 | 0 | 0 |
| Rousse, 2015 [45] | 32 | 30 (93.8) | 9 | 28.1 | 30 | |||
| Thiagarajan, 2009 [46] | 297 | 216 (72.7) | 61 | 20.5 | 28.2 | |||
| Total e-CPR | 644 | 523 (81.2) | 136 | 21.9 [16.6–27.5]* | 27.9 [19.7–36.6]* | 11 | 29.4 [4.3–60.8] | 7.6 [0.5–17.8] |
| Overall | 23,388 | 17,779 (76.0) | 1830 | 8.9 [7.0–11.0] | 12.6 [10.2–15.2] | 196 | 41.8 [20.2–51.0] | 5.8 [2.1–10.9] |
Pooled rates are reported in italics as point estimate (95 %CIs)
c-CPR conventional cardiopulmonary resuscitation, e-CPR extracorporeal cardiopulmonary resuscitation
p < 0.0001 vs. c-CPR