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. 2016 Oct 19;6:35531. doi: 10.1038/srep35531

Figure 1. Loss of SRA increases the hepatic ATGL expression.

Figure 1

(a) RT-qPCR analysis of mRNA expression of FFA oxidation, lipogenesis and VLDL metabolism-related genes in livers of male SRAKO (KO, n = 8) or WT (n = 8) littermates (20 weeks of age) fed with normal chow. (b) Hepatic mRNA level of ATGL in SRAKO (KO, n = 8) or WT (n = 8) littermates (20 weeks of age) fed with normal chow or HFD. The mRNA levels of genes were normalized to 36B4 expression. The data are presented as the mean ± SE and expressed as fold-change relative to the level of WT-Chow. *p < 0.05. (c) Liver lysates from male SRAKO (KO) or WT littermates (20 weeks of age) under different diet conditions were immunoblotted with anti-ATGL and anti-β-actin antibodies.