Mutual interference of LPS and PPVO. PBMC were stimulated for 24 h with the substances noted in the upper row of the x axis, namely, RPMI 1640 medium as a negative (neg.) control, a low dose of LPS (100 pg/ml), or PPVO (virus titer, 104.6/ml). This stimulation was followed by a second stimulation for 4 h with the substances noted in the second row, namely, RPMI 1640 medium as a negative control, a high dose of LPS (100 ng/ml), or PPVO (virus titer, 104.6). For stimulation with PPVO prior to LPS and LPS prior to PPVO, the results for only three donors (don.) are shown, while for the other items, data for five donors were available.