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The presence of BPI has no influence on TNF-α induction by PPVO. PBMC (106/ml) were stimulated with LPS (100 pg/ml) and PPVO (virus titer, 104.6/ml) alone or in the presence of BPI (10 μg/ml) for 24 h. BPI abolished TNF-α induction after LPS treatment but not after PPVO treatment. The TNF-α levels of the LPS-stimulated samples significantly exceeded the other values and are shown beside the columns.
