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Summary of Incidence of Hyperemia by Treatment Group and Time point—All Stages (%)
| Screening | Day −4 | Day −1 | Day 1-predose | Day 1-postdose | Day 14 | Day 28 | |
|---|---|---|---|---|---|---|---|
| Placebo | 8.5 | 3.4 | 1.7 | 3.4 | 0.6 | 3.5 | 3.8 |
| 50 mcg | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 100 mcg | 5.9 | 5.9 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 200 mcg | 0.0 | 0.0 | 0.0 | 0.0 | 2.0 | 1.0 | 0.0 |
| 500 mcg | 14.7 | 11.8 | 12.5 | 11.8 | n/a | 12.7 | 12.1 |
