Table 4.
Association of Antiretroviral Therapy (ART) Adherence and Virologic Suppression with Nonlipid Cardiovascular Disease (CVD) Risk Factor Management, Women's Interagency HIV Study (WIHS) Participants, 2006–2014
| CVD risk factor management outcome, as related to ART adherence (95% of time) | n person-visits (n women), adherent | % with outcome, adherent | n person-visits (n women), not adherent | % with outcome, not adherent | Rate ratio for adherence (95% CI) | p Value |
|---|---|---|---|---|---|---|
| Hypertension treatment | 4193 (783) | 78 | 817 (349) | 74 | 1.03 (0.95–1.11) | 0.47 |
| Hypertension control | 4193 (783) | 69 | 817 (349) | 65 | 0.99 (0.92–1.07) | 0.82 |
| Diabetes treatment | 2593 (294) | 51 | 473 (165) | 51 | 0.98 (0.87–1.12) | 0.78 |
| Diabetes control | 1084 (254) | 75 | 193 (105) | 70 | 1.24 (0.99–1.54) | 0.06 |
| Smoking cessation | 3628 (619) | 10 | 914 (353) | 8 | 1.11 (0.87–1.42) | 0.40 |
| CVD risk factor management outcome, as related to virologic suppression | n person-visits (n women), suppressed | % with outcome, suppressed | n person-visits (n women), not suppressed | % with outcome, not suppressed | Rate ratio for suppression (95% CI) | p Value |
|---|---|---|---|---|---|---|
| Hypertension treatment | 2654 (638) | 80 | 855 (413) | 73 | 1.07 (1.01–1.13) | 0.03 |
| Hypertension control | 2654 (638) | 72 | 855 (413) | 62 | 1.13 (1.04–1.22) | 0.003 |
| Diabetes treatment | 1506 (254) | 58 | 472 (192) | 50 | 1.08 (0.97–1.21) | 0.16 |
| Diabetes control | 627 (206) | 74 | 197 (126) | 64 | 1.11 (0.95–1.28) | 0.18 |
| Smoking cessation | 1929 (449) | 10 | 777 (366) | 9 | 1.06 (0.76–1.48) | 0.72 |
Exposed and unexposed person-visits after on 1:1 propensity score matching with replacement, accounting for age at visit, race/ethnicity, year of visit, current income, education, current employment, current insurance status, study site, CD4+ count, viral load, history of ART, number of children, change in number of children since last visit, history of recreational drug use, current recreational drug use, history of alcohol use, current alcohol use, current stable housing, depressive symptoms. Rate ratios determined by weighted log-binomial regression with robust variance.
CI, confidence interval.