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Run time performance for all benchmarked software. All tests were performed using 1 to 32 cores on Intel Xeon CPU E5-2640 v3 at 2.60 GHz. Input files contained reads subsampled from the Global Gut. For serial performance, some tools do not show results for 108 reads due to exceeding wall time limit (230 h) or failed memory allocation. For parallel performance, a single file containing 1 million Illumina sequences was used over multiple threads.
