Table 1. Clinical features of the 36 WS probands.
| Proband | Gender | Age (years) | Dystopia canthorum | Pigmentary abnormalities* | Hearing loss | WS subtype | Family history of WS |
|---|---|---|---|---|---|---|---|
| W2-1 | M | 9 | Yes | E | Profound | WS1 | No |
| W9-1 | F | 16 | Yes | E | Profound | WS1 | Yes |
| W22-1 | M | 5 | Yes | E | Severe | WS1 | No |
| B5-1 | M | 5 | Yes | E | Profound | WS1 | No |
| W24-1 | F | 4 | Yes | E | Profound | WS1 | Yes |
| D3-1 | M | 5 | Yes | E+P | Profound | WS1 | No |
| W28-1 | M | 1 | Yes | E | Profound | WS1 | Yes |
| W3-1 | M | 18 | No | E+W+P | Profound | WS2 | Yes |
| W4-1 | F | 13 | No | E | Profound | WS2 | Yes |
| W8-1 | M | 17 | No | E | Profound | WS2 | No |
| W10-1 | F | 19 | No | E | Profound | WS2 | No |
| W11-1 | F | 18 | No | E | Profound | WS2 | No |
| W12-1 | F | 2 | No | E | Profound | WS2 | Yes |
| W17-1 | M | 1 | No | E | Profound | WS2 | No |
| W23-1 | M | 5 | No | E | Profound | WS2 | No |
| D680-1 | M | 1 | No | E | Profound | WS2 | Yes |
| W25-1 | M | 9 | No | E | Profound | WS2 | No |
| W26-1 | M | 2 | No | E+P | Profound | WS2 | No |
| W27-1 | M | 4 | No | E | Profound | WS2 | No |
| W47-1 | M | 1 | No | E+F | Profound | WS2 | No |
| W14-1 | F | 15 | No | E+W +F+P | Profound | WS2 | Yes |
| W16-4 | M | 27 | No | W+F | Profound | WS2 | Yes |
| W18-1 | F | 31 | No | E+W+F | Profound | WS2 | Yes |
| W19-1 | M | 3 | No | E+F | Profound | WS2 | Yes |
| W21-1 | M | 31 | No | W+F | Profound | WS2 | No |
| D2-1 | M | 3 | No | E | Profound | WS2 | Yes |
| W33-1 | M | 3 | No | E | Profound | WS2 | Yes |
| W44-1 | F | 8 | No | F | Profound | WS2 | Yes |
| W46-1 | M | 6 | No | E+P | Profound | WS2 | Yes |
| D50-1 | F | 4 | No | E | Profound | WS2 | No |
| W1-1 | F | 7 | No | E | Profound | WS2 | No |
| W7-1 | F | 11 | No | E+W | Profound | WS2 | No |
| B118-1 | M | 3 | No | E | Profound | WS2 | No |
| W31-1 | M | 60 | No | E | Profound | WS2 | Yes |
| D13-1 | M | 3 | No | E+P | Profound | WS2 | No |
| W15-1 | M | 1 | No | E | Profound | WS2 | No |
*E: heterochromiairidum; W: premature whitening of the hair; F: excessive freckles; P: Patchy skin depigmentation.