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. 2016 Oct 19;9:112. doi: 10.1186/s13045-016-0342-6

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Expression of MIIP is reduced in human EC specimens. a MIIP expression was evaluated by immunohistochemical staining on TMAs. The respective images in the same TMAs showed that MIIP expression was lower in EC than those in NE and AHE. b Statistical analysis revealed that MIIP expression was highest in NE, lower in AHE, and lowest in EC. c Loss expression of MIIP was related to lymph node metastasis in EC. Left panel: Shown are representative images of MIIP expression in EC tissues with or without lymph node metastasis. Right panel: Statistical analysis revealed that low MIIP expression was correlated with lymph node metastasis in EC patients. Asterisk indicates P < 0.05. See also Table 1